Dr. Hertzberg is a Professor, tenured, and is an internationally-recognized expert on "big data" and its impact on health care. She is widely known for her work measuring the social contacts in emergency departments and disease transmission on airplanes. Her research has been funded by the National Library of Medicine, National Institute of Neurological Disorders and Stroke, the National Institute of Environmental Health, and the National Institute of Allergy and Infectious Disease. Her work has been published in high-impact journals, including the Proceedings of the National Academy of Science, New England Journal of Medicine, PLOS One, and Pediatrics.